Research Article

Antihypertensive Activity of Leersia hexandra Sw. (Poaceae) Aqueous Extract on Ethanol-Induced Hypertension in Wistar Rat

Table 3

Effects of aqueous extract of L. hexandra on lipid parameters.

ParametersNTRHTRNif. 10L h 100L h 200

TC (mg/dL)149.36 ± 8.05224.02 ± 5.453154.98 ± 11.20184.09 ± 7.59176.98 ± 6.62
TG (mg/dL)63.74 ± 0.63100.34 ± 0.38367.99 ± 0.2069.86 ± 1.8364.13 ± 0.23
LDL-Chol (mg/dL)76.04 ± 9.51175.12 ± 5.74389.14 ± 9.42139.11 ± 7.51122.56 ± 7.02
HDL-Chol (mg/dL)60.58 ± 2.4129.01 ± 0.50352.24 ± 1.2831.01 ± 0.68341.59 ± 0.65
Atherogenic index2.49 ± 0.217.72 ± 0.1432.96 ± 0.155.95 ± 0.303.74 ± 0.12

Each value represents the mean ± SEM (n = 5). TC: total cholesterol, LDL-Chol: LDL-cholesterol, HDL-Chol: HDL-cholesterol, TG: triglycerides, and NTR: normotensive rats receiving distilled water (10 mL/kg), HTR: hypertensive rats receiving distilled water (10 mL/kg) and ethanol (5 g/kg), L h 100 and L h 200: hypertensive rats receiving ethanol and Leersia hexandra extract at doses of 100 and 200 mg/kg, and Nif. 10: hypertensive rats receiving ethanol and nifedipine at the dose of 10 mg/kg; 1: p <0.05, 2: p <0.01, and 3: p <0.001: significant difference from normotensive rats; a: p <0.05, b: p <0.01, and c: p <0.001: significant difference compared to hypertensive rats.