Antihypertensive Activity of Leersia hexandra Sw. (Poaceae) Aqueous Extract on Ethanol-Induced Hypertension in Wistar Rat

Table 4

Effects of the aqueous extract of Leersia hexandra on liver and kidney functions.

Parameters	NTR	HTR	Nif. 10	L h 100	L h 200
ALT (U/L)	22.84 ± 1.29	30.56 ± 2.24^2	15.71 ± 0.95	17.90 ± 0.62	11.06 ± 0.49
AST (U/L)	133.47±2.13	327.01±1.45^3	175.18 ±7.28	241.04 ±13.73	239.78±0.59
Creatinine (mg/dL)	1.77 ± 0.15	7.86 ± 0.49^3	2.57 ± 0.40	0.73 ± 0.28	1.71 ± 0.20

Each value represents the mean ± SEM (n = 5). NTR: normotensive rats receiving distilled water (10 mL/kg), HTR: hypertensive rats receiving distilled water (10 mL/kg) and ethanol (5 g/kg), L h 100 and L h 200: hypertensive rats receiving ethanol and Leersia hexandra extract at doses of 100 and 200 mg/kg, and Nif. 10: hypertensive rats receiving nifedipine at the dose of 10 mg/kg; 2: p <0.01 and 3: p <0.001: significant difference compared to the normal control; c: p <0.001: significant difference compared to hypertensive rats.