Susceptibility of Toxoplasma gondii to Ethanolic Extract of Tinospora crispa in Vero Cells

Figure 3

The cytotoxicity and antiparasitic graphs demonstrating 50% inhibitory concentrations. Cytotoxicity graphs of alkaloids (a), clindamycin (b), and EETC (c) each with IC₅₀ = 60.4 ± 2.7 μg/mL, 116.5 ± 2.3 μg/mL, and 179.0 ± 1.5 μg/mL, respectively, are shown. The antiparasitic activities of the alkaloids (d), clindamycin (e), and EETC (f) each with IC₅₀ = 14.25 ± 0.9 μg/mL, 8.33 ± 1.04 μg/mL, and 6.31. ± 1.4 μg/mL, respectively, are also shown. The selectivity index (SI) for alkaloids is 4.2 and clindamycin is 13.9, while that of EETC is 28.4.

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