Research Article

Genome Damage in Rats after Transplacental Exposure to Jatropha dioica Root Extract

Table 3

Weight and number of offsprings in new born rats from mothers treated with J. dioica during pregnancy.

Study groupsWeight (g)Number of offsprings

Negative control (n = 6)5.76 ± 0.486.43 ± 2.99

J. dioica: low dose 60 mg/kg6.0 ± 0.306.17 ± 2.63
NS

J. dioica: middle dose 100 mg/kg6.33 ± 0.475.43 ± 2.50
NS

J. dioica: high dose 300 mg/kg5.56 ± 0.507.50 ± 4.32
NS

Positive control4.85 ± 0.488.0 ± 2.82

Data are expressed as mean ± SD; NS: not significant; n: sample size (pregnant rats/6 pups per dam). All study groups were compared with the negative control.