A Network Pharmacology Approach to Uncover the Molecular Mechanisms of Herbal Formula Kang-Bai-Ling for Treatment of Vitiligo

Figure 3

KBL shared 15 potential targets with known pathological course related targets of vitiligo. (a) The compound potential target network was constructed by linking the overlapped targets (between KBL potential and known vitiligo-related) and the homologous candidate compounds of KBL. The nodes representing candidate compounds are shown as pink triangle and the targets are presented as purple circular. (b) 15 overlapped targets (between KBL potential and known vitiligo-related) was performed in Omicshare to gain more insights into their involvement in various GO terms. We considered a value cutoff of ≤0.05 as significant and applied hypergeometric test to identify enriched GO terms. Following chart shows an overview of the gene ontology analysis with up to 20 significantly enriched terms. (c) 15 overlapped targets (between KBL potential and known vitiligo-related) was performed in Omicshare to gain more insights into their involvement in KEGG pathways.

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