Lycopus lucidus Turcz Inhibits the Osteoclastogenesis in RAW 264.7 Cells and Bone Loss in Ovariectomized Rat Model

Figure 7

wLL inhibits bone loss of trabecular area in OVX-induced osteoporosis rats. (a) Representative histological image of femoral head from OVX-induced osteoporosis rat using H&E staining. Sham group: sham operated group, OVX group: ovariectomized group, E2 group: administration of 17β-estradiol at 100 μg/kg after OVX, wLL-L group: administration of wLL at 15.2 mg/kg after OVX, and wLL-H group: administration of wLL at 152 mg/kg after OVX. Scale bars are 500 μm (40x) and 200 μm (100x). (b) Trabecular area measured using Image J software. Data represent the mean ± SEM of eight independent experiments.

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