Panax ginseng Inhibits Metabolism of Diester Alkaloids by Downregulating CYP3A4 Enzyme Activity via the Pregnane X Receptor

Figure 1

Concentrations of aconitine (a), mesaconitine (b), and hypaconitine (c) in the liver microsome incubation system after oral administration of P. ginseng. Compared with the control group, < 0.05; < 0.01 (n = 3). Ginseng-L: P. ginseng low group; Ginseng-M: P. ginseng middle group; Ginseng-H: P. ginseng high group.

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(b)

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