Panax ginseng Inhibits Metabolism of Diester Alkaloids by Downregulating CYP3A4 Enzyme Activity via the Pregnane X Receptor

Figure 2

Blood concentration-time curves of probe drugs after administration of P. ginseng. Blood concentration-time curves of midazolam (a), caffeine (b), tolbutamide (c), and chlorzoxazone (d) of rats after oral administration of P. ginseng for 7 days. Ginseng-L: P. ginseng low group; Ginseng-M: P. ginseng middle group; Ginseng-H: P. ginseng high group.

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(b)

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