MicroRNAs in the Progress of Diabetic Nephropathy: A Systematic Review and Meta-Analysis
Table 1
Main characteristics of the reports included in the study; expression of miRNAs in DN groups.
Author
Year
Country
Methods
Samples
Case Number
MiRNAs
Expression
N
NA
MA
MAA
McClelland et al.
2015
Australia
qRT-PCR
FFPE
35
8
miR-21
up
Huang et al.
2014
China
qRT-PCR
biopsy
3
6
miR-155,miR-146a
up
Koga et al.
2015
Japan
qRT-PCR
biopsy
11
miR-26a
down
Eissa et al.
2016
Egypt
qRT-PCR
urinary exosomes
54
56
66
44
miR-133b,miR-342,miR-30
up
Bijkerk et al.
2015
Netherlands
qRT-PCR
plasma
19
21
miR-181a,miR-326
up
miR-223,miR-574-3p
down
Federica
2015
Italy
qRT-PCR
urinary exosomes
12
12
miR-145,miR-130a
up
miR-155,miR-424
down
Kafaji et al.
2016
Bahrain
qRT-PCR
whole blood
50
29
21
miR-126
down
Ma et al.
2016
China
qRT-PCR
serum
127
157
159
148
miR-192
down
Jia et al.
2016
China
qRT-PCR
urinary
10
30
20
30
miR-192,miR-194,miR-215
up
Barutta et al.
2016
Italy
qRT-PCR
serum
143
74
105
miR-126
down
Shao et al.
2016
China
qRT-PCR
serum
195
186
169
140
miR-217
up
Eissa et al.
2016
Egypt
qRT-PCR
urinary exosomes
44
46
90
miR-15b,miR-34a,miR-636
up
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