Gastroprotective Effects of Paeonia Extract Mixture HT074 against Experimental Gastric Ulcers in Rats

Table 1

Effects of HT074 on gastric secretion in pylorus-ligated rats.

Groups	Volume (mL)	Acidity (μEq/mL)	Total acidity (μEq/4h)
Control	7.70 ± 0.32	118.33 ± 8.50	908.83 ± 77.74
Omeprazole 20 mg/kg	4.38 ± 0.4	30.00 ± 1.5	128.17 ± 8.4
HT074 100 mg/kg	6.53 ± 0.45	102.50 ± 0.09	676.17 ± 66.69
HT074 300 mg/kg	5.37 ± 0.3	93.33 ± 5.5	511.17 ± 61.7

The volume, acidity, and total acidity of the gastric juice were measured after 4 h of pylorus ligation in rats. Values are expressed as mean ± SEM. n=6 per group. < 0.05, < 0.01, and < 0.001 vs. control by ANOVA with Dunnett’s post hoc test.