Review Article

Metabolic and Epigenetic Action Mechanisms of Antidiabetic Medicinal Plants

Figure 5

An overview of the main epigenetic mechanisms and their association with diabetes. Inhibitors/activators of the several epigenetic marks were shown to alleviate the effects or symptoms of diabetes via several routes. Details for such mechanisms are in the main text. LSDi: lysine-specific demethylase inhibitor; DNMTi: DNA-methyltransferases inhibitor; HATi: histone Acetyltransferase inhibitor; HDACi: histone deacetylase inhibitor; CH3: methyl group; AC: acetyl group.