Research Article

In Vitro Anti-Inflammatory and In Vivo Antiarthritic Activities of Aqueous and Ethanolic Extracts of Dissotis thollonii Cogn. (Melastomataceae) in Rats

Figure 2

Histopathological analysis of ankle joints stained with H&E. (a) Healthy control showing normal structure with small joint space; (b) Arthritic control showing very large joint space (A), erosion of articular cartilage (B), and bone erosion (C), (c) diclofenac 5 mg/kg treated, (d) aqueous extract (AE) 500 mg/kg treated, and (e) ethanolic extract (EE) 500 mg/kg treated showing a decrease in joint space, erosion of the synovial membrane and a reduction of erosion of articular cartilage.
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