In Vitro Anti-Inflammatory and In Vivo Antiarthritic Activities of Aqueous and Ethanolic Extracts of Dissotis thollonii Cogn. (Melastomataceae) in Rats

Table 4

Influence of the aqueous and ethanolic extracts of Dissotis thollonii on haematological in CFA-induced arthritis in rats.

Treatment	Dose (mg/kg)	Haemoglobin (g/dl)	Hematocrit (%)	Platelet (10^9/L)	RBC (million/μl)	WBC (10^9/L)
Healthy control	—	16.40 ± 0.73	38.78 ± 1.03	365.25 ± 26.23	7.22 ± 0.34	7.85 ± 0.44
Arthritic control	—	9.43 ± 0.20^λ	25.65 ± 1.27^λ	554.75 ± 21.54^λ	3.90 ± 0.37^λ	13.78 ± 0.56^λ
Diclofenac	5	14.15 ± 0.62^b	33.88 ± 2.59^a	481.75 ± 13.31^β	5.65 ± 0.24^a	10.63 ± 0.64^αa
Aqueous extract	250	14.28 ± 0.67^b	31.15 ± 1.23^α	478.74 ± 18.71^β	5.74 ± 0.40^a	11.85 ± 0.80^λ
	500	15.55 ± 0.59^c	37.73 ± 1.28^c	383.50 ± 9.75^c	6.93 ± 0.25^c	10.25 ± 0.41^b
Ethanolic extract	250	14.33 ± 1.02^b	32.20 ± 1.70	426.00 ± 18.11^c	6.31 ± 0.38^c	11.15 ± 0.48^β
	500	16.88 ± 1.32^c	38.38 ± 0.99^c	374.75 ± 8.28^c	7.36 ± 0.29^c	8.28 ± 0.42^c

CFA: complete Freund’s adjuvant; RBC: red blood cell; WBC: white blood cell. Each value represents the mean ± ESM of six animals. ^α; ^β; ^λ statistically significant compared with the healthy control. Each value represents the mean ± ESM of 6 animals. ^a; ^b; ^c statistically significant compared to arthritic control.