Integrated Metabolomics and Network Pharmacology Study on Immunoregulation Mechanisms of Panax ginseng through Macrophages

Figure 3

Score plots of control group, groups treated with PG extract in different concentrations, and QC from PCA in the ESI− mode (a) and ESI+ mode (b). QC indicates the quality control group. OPLS-DA analysis of the data derived from the ESI- mode. OPLS-DA score plots (c, d) and S-plot of the OPLS-DA model (e, f) for the pair-wise comparisons between the control and high-dose group of PG. The axes that are plotted in the S-plot from the predictive component are p1 vs. p(corr)1, representing the magnitude (modelled covariation) and reliability (modelled correlation), respectively. The points in red indicated the identified potential biomarkers.

(a)

(b)

(c)

(d)

(e)

(f)