Research Article

Biological Properties and Bioactive Components of Mentha spicata L. Essential Oil: Focus on Potential Benefits in the Treatment of Obesity, Alzheimer’s Disease, Dermatophytosis, and Drug-Resistant Infections

Table 4

FIC and interaction effects of double combinations of EO or carvone with orlistat on pancreatic lipase inhibitory activities.

Combination (A/B)MIC50 A (alone) (μL/mL)MIC50 B (alone) (μg/mL)MIC50 A (in the presence of B) (μL/mL)MIC50 B (in the presence of A) (μg/mL)Checkerboard FIC index

EO/orlistat12.50.0320.0780.00390.11
Carvone/orlistat12.50.0320.0780.00190.065