Tetrahydroxystilbene Glucoside Suppresses NAPDH Oxidative Stress to Mitigate Apoptosis and Autophagy Induced by Cerebral Ischemia/Reperfusion Injury in Mice

<p>TSG injection reduced cerebral infarct volume proportion and improved neurological score. The brain tissues of ischemic penumbra were collected at 24h after MCAO. (a) The black frame indicated samples dissection and collection at the ischemic penumbra in the cortex and hippocampus around the ischemic boundary in this study. (b) Representative HE staining images of brain cortex and hippocampus in each group showed the pathological changes in ischemic penumbra (n=4). (c) Representative TCC staining graph of brain tissues in each group. (d) Cerebral infarct volume proportion in each group (n=6). (e) Longa neurological score in each group. Data are mean± SEM (n=6). ∗∗p&lt;0.01 compared with I/R group.</p>

Evidence-Based Complementary and Alternative Medicine

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Figure 1: Tetrahydroxystilbene Glucoside Suppresses NAPDH Oxidative Stress to Mitigate Apoptosis and Autophagy Induced by Cerebral Ischemia/Reperfusion Injury in Mice 

Figure 1 | Tetrahydroxystilbene Glucoside Suppresses NAPDH Oxidative Stress to Mitigate Apoptosis and Autophagy Induced by Cerebral Ischemia/Reperfusion Injury in Mice 