Research Article
In a Rat Model of Acute Liver Failure, Icaritin Improved the Therapeutic Effect of Mesenchymal Stem Cells by Activation of the Hepatocyte Growth Factor/c-Met Pathway
Figure 3
ICT protects MSCs from hydrogen peroxide-induced cell death and the expression of apoptosis-related proteins. (a) The effect of different concentrations of ICT on the viability of hydrogen peroxide treated MSCs. (b) Detection of protein levels of cleaved caspase-3, Bcl-2, and Bax in MSCs as judged by western blot. (c) Detection of mRNA expression levels of caspase-3, Bcl-2, and Bax in MSCs by qRT-PCR. ∗P < 0.05 vs. control. Data are means ± SD. Each experiment was replicated 3 times.