Jwa Kum Whan Attenuates Nonalcoholic Fatty Liver Disease by Modulating Glucose Metabolism and the Insulin Signaling Pathway

Figure 1

Effects of JKW on intracellular TG and TC and on lipid accumulation in HepG2 cells. (a) Cell viability was determined using the MTT-based Ez-cytox assay. Cells were treated with different concentrations of JKW extract (10, 25, 50, 75, or 100 μg/mL) for 24 h. Results are expressed as percentages of untreated controls. (b) Intracellular TG and (c) TC contents were measured as described in Materials and Methods. (d) Lipid accumulation was determined using an Oil Red O assay. Results are the means ± SDs of three independent experiments. < 0.01 vs. untreated controls and < 0.01 vs. FFA-treated controls.

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