Research Article
Mechanisms of Compound Kushen Injection for the Treatment of Lung Cancer Based on Network Pharmacology
Table 1
The docking information of 7 targets with corresponding compounds.
| Number | Target | PDBID | Compound | CID | Docking score |
| 1 | CHRNA3 | 4ZK4 | isomatrine | 5271984 | 6.802 | baptifoline | 621307 | 6.787 | matrine | 91466 | 6.783 | sophoridine | 165549 | 6.731 | lamprolobine | 87752 | 6.123 | N-methylcytisine | 670971 | 6.069 |
| 2 | DRD2 | 2HLB | baptifoline | 621307 | 6.616 | sophocarpine | 115269 | 6.486 | N-methylcytisine | 670971 | 6.370 |
| 3 | PRKCA | 4RA4 | 9α-hydroxymatrine | 15385684 | 6.657 | sophoranol | 12442899 | 6.635 | adenine | 190 | 6.058 |
| 4 | CDK1 | 5LQF | macrozamin | 9576780 | 6.111 | adenine | 190 | 5.385 |
| 5 | CDK2 | 2R3I | macrozamin | 9576780 | 5.933 | adenine | 190 | 5.712 |
| 6 | MMP1 | 1SU3 | adenine | 190 | 5.508 | oxymatrine | 114850 | 5.371 |
| 7 | MMP9 | 1ITV | adenine | 190 | 6.068 | matrine | 91466 | 5.464 |
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