Ligustrum robustum Intake, Weight Loss, and Gut Microbiota: An Intervention Trial

Table 3

Metabolic variables at baseline and 12 wk after Ligustrum robustum intervention.

Biomarkers	Baseline	12 wk	P
Lipid profile
TG, mmol/L	1.57±0.96	1.48±0.87	0.33
CHOL, mmol/L	4.75±0.74	4.72±0.95	0.81
LDL cholesterol, mmol/L	3.00±0.77	3.06±0.80	0.67
HDL cholesterol, mmol/L	1.33±0.27	1.42±0.33	0.01
Glucose metabolism
Glucose, mmol/L	5.45, 0.85	5.27, 0.71	<.01
Insulin, mU/L	9.50, 6.14	9.84, 4.75	0.48
C-Peptide, pmol/mL	0.77, 0.41	0.77, 0.39	0.09
HOMA-IR	2.42, 2.56	2.24, 1.41	0.87
HOMA-β, %	87.53, 50.88	103.99, 62.66	<.01
Cytokines and hormones
IL6, pg/mL	0.86, 0.47	0.68, 0.79	0.39
IL8, pg/mL	6.04, 4.21	4.79, 2.45	0.02
Leptin, pg/mL	6856.5, 5203.25	5628, 3290.25	<.01
Safety assessment
Total protein, g/L	73.67±3.94	73.99±4.36	0.48
Globulin, g /L	28.36±3.27	28.39±3.42	0.91
Albumin/Globulin (A/G)	1.62±0.19	1.63±0.18	0.58
ALB, g/L	45.31±1.79	45.60±1.86	0.30
ALT, U/L	30.90±20.49	22.43±9.76	0.02
AST, U/L	27.57±11.80	22.03±7.35	0.01
GGT, U/L	31.37±27.48	25.37±20.77	0.18
DBIL, umol/L	3.70±1.24	3.63±1.09	0.75
IDBIL, umol/L	6.17±2.57	6.50±2.54	0.55
TBIL, umol/L	9.87±3.71	10.13±3.55	0.73
UREA, mmol/L	5.30±1.33	5.44±1.37	0.59

Data with normal distribution are presented as mean ± SD and data with nonnormal distribution are presented as median, interquartile range.
P values were calculated by paired T test for normal distribution variables and Wilcoxon signed-rank test for nonparametric tests.
ALB, albumin; ALT, alanine aminotransferase; AST, aspartic transaminase; CHOL, total cholesterol; DBIL, direct bilirubin; GGT, gamma-glutamyl transferase; HDL, high-density lipoprotein cholesterol; LDL, low-density lipoprotein cholesterol; TBIL, total bilirubin; TG, triglycerides; IDBIL, Indirect bilirubin.
P<0.05.