Phikud Navakot Modulates the Level of Pro-Inflammatory Mediators and the Protein Expression of SOD1 and 2 and the Nrf2/HO-1 Signaling Pathway in Rats with Acute Myocardial Infarction
Effect of 28-day pretreatment with PN formula on histopathological changes. (a) Representative photomicrographs of cardiac tissues of the control, IMI, IMI pretreated with Pro, normal and IMI pretreated with PN (64, 127, or 255 mg/kg). IMI showed myocardial ischemia with inflammatory cell infiltration () and interstitial edema (). Scale bar: 50 μm. (b) The degree of histopathological changes of the cardiac tissues has plotted a histogram. Values are expressed as mean ± SD (n = 5), vs. the control. vs. the IMI rat.
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