Oxidative Stress and TGF-β1/Smads Signaling Are Involved in Rosa roxburghii Fruit Extract Alleviating Renal Fibrosis

Figure 6

Cili decreases the protein expression of members of the TGF-β signaling pathway in kidneys after UUO. Representative immunohistochemistry images of key proteins in the TGF-β signaling in kidneys are shown with quantification. Scale bar: 10 μm. Positive staining is indicated by arrows. N=12/group. The results are expressed as mean ± SD. P<0.01 vs. the sham group; △△P<0.01 vs. the UUO group; ◆◆P<0.01 vs. the losartan group.