Identification of Chinese Herbal Compounds with Potential as JAK3 Inhibitors

Figure 3

Analysis of Chinese herbal compound binding to JAK3 kinase. (a) CP-690550; (b) Cryptotanshinone; (c) Icaritin; (d) Indirubin. JAK3 kinase is depicted in marine-blue ribbon. Chemicals are shown as sticks & balls and transparent solids. JAK3 protein-ligand interactions were mapped using Ligplot+. CP-690,550 was the positive control.