Cytoprotective Effect of Ligustrum robustum Polyphenol Extract against Hydrogen Peroxide-Induced Oxidative Stress via Nrf2 Signaling Pathway in Caco-2 Cells
Table 3
Effects of BuE with various doses on the marker of oxidative stress in Caco-2 cells.
Blank
H2O2
BuE + H2O2
162.5 mg/l
81.3 mg/l
40.6 mg/l
MDA (nmol/g protein)
0.36±0.15
0.82±0.19##
0.33±0.11
0.56±0.16
0.64±0.11
GSH (μmol/g protein)
51.52±2.85
28.59±4.58##
52.21±3.94
43.65±0.82
39.95±2.30
TAOC (mmol /g protein)
0.41±0.01
0.22±0.01##
0.31±0.01
0.34±0.01
0.28±0.01
SOD (U/mg protein)
21.48±1.86
27.66±1.46##
30.47±1.99
36.93±2.16
33.76±1.05
CAT (U/mg protein)
26.20±0.23
16.72±0.30##
22.18±0.98
29.83±1.03
25.11±0.83
GSH-Px (mU/mg protein)
3.75±0.23
2.70±0.36##
4.87±0.32
4.15±0.27
3.69±0.31
GR (mU/mg protein)
3.14±0.43
3.36±0.14
4.59±0.21
3.83±0.12
3.63±0.28
Data are shown as means ± SD (n = 6). BuE: n-butanol extract. ##p < 0.01 versus blank. p < 0.05 versus H2O2. p < 0.01 versus H2O2
