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Study ID | Sample size | Gender (male/female) | Age | Course of disease/year | Syndrome differentiation of | Intervention | Course of treatment/ weeks | Outcome |
T | C | T | C | T | C | T | C | TCM | T | C |
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Chen HL 2016 | 13 | 13 | 8/5 | 9/4 | 60.4 ± 5.9 | 59.7 ± 6.3 | 2.1 ± 0.6 | 2.3 ± 0.4 | NA | Yiqi Tongluo Jiedu decoction | NAC | 12 | ④⑤ |
Xin DY 2016 | 25 | 24 | 15/10 | 14/10 | 65.68 ± 7.50 | 65.88 ± 7.51 | 0.94 ± 0.35 | 0.93 ± 0.44 | qi deficiency and blood stasis | Erjia-xiaozheng decoction | NAC | 12 | ③⑤ |
Zhao GJ 2016 | 24 | 18 | 15/9 | 13/5 | 58.84 ± 18.53 | 59.52 ± 19.35 | 1.97 ± 1.38 | 2.16 ± 1.88 | deficiency of both qi and yin, phlegm and static blood obstructing lung | Fuzheng-huaxian decoction | NAC | 12 | ③④⑤⑥⑦ |
Zhao GJ 2018 | 30 | 30 | 18/12 | 16/14 | 58 | 59 | 1.97 ± 1.38 | 2.16 ± 1.88 | deficiency of both qi and yin, phlegm and static blood obstructing lung | Fuzheng-huaxian decoction | NAC | 12 | ③④⑤⑦ |
Fan MR 2012 | 22 | 21 | 14/8 | 12/9 | 60.98 ± 9.22 | 65.12 ± 8.61 | 4.21 ± 1.98 | 3.73 ± 2.25 | deficiency of both qi and yin, lung collaterals obstruction | Feixiantong decoction+ CM | NAC+ CM | 12 | ③④⑤⑦ |
Fan CZ 2013 | 20 | 20 | 13/7 | 11/9 | 65 ± 9.46 | 68.1 ± 12.15 | NA | NA | deficiency of both qi and yin, lung collaterals obstruction | Buxu Tongbi decoction + CM | NAC+ CM | 12 | ③⑤⑦ |
Li ZH 2015 | 34 | 30 | 18/16 | 14/16 | 58.23 ± 8.35 | 59.98 ± 7.43 | 2.38 ± 0.45 | 2.87 ± 0.12 | deficiency of both qi and yin, phlegm and static blood obstructing lung | Yangyin Yifei Tongluo pill+ CM | NAC+ CM | 12 | ④⑤ |
An SY 2017 | 30 | 30 | 14/16 | 13/17 | 66.8 ± 9.3 | 61.5 ± 8.7 | 3.6 ± 0.9 | 3.2 ± 0.8 | qi deficiency and blood stasis | Jiawei-xiayuxue decoction + NAC | NAC | 24 | ③④⑤ |
Liu M 2015 | 18 | 16 | NA | NA | NA | NA | NA | NA | qi deficiency and blood stasis | Xuefu-zhuyu capsule +NAC | NAC | 72 | ①②④⑤⑥⑦ |
Wang QJ 2016 | 43 | 37 | 23/20 | 19/18 | 60.51 ± 6.82 | 59.23 ± 6.91 | 22.32 ± 8.28 | 20.28 ± 6.81 | yang deficiency and blood stasis | Wenyang-huayu decoction +NAC | NAC | 12 | ④ |
Bao XY 2014 | 30 | 30 | 18/12 | 16/14 | 64.90 ± 10.25 | 65.47 ± 12.71 | 4.2 ± 1.50 | 4.3 ± 1.47 | deficiency of both qi and yin, phlegm and static blood obstructing lung | Kangxian granule +NAC+ CM | NAC+ CM | 12 | ④⑦ |
Yan XX 2015 | 60 | 60 | 34/26 | 35/25 | 63.5 ± 1.2 | 63.4 ± 1.3 | 1.03 ± 0.1 | 1.04 ± 0.11 | qi deficiency and blood stasis | Buyang-huanwu decoction +NAC+ CM | NAC+ CM | 24 | ④⑦ |
Fan MR 2015 | 27 | 28 | 17/11 | 18/9 | 62.36 ± 10.5 | 65.68 ± 10.29 | NA | NA | deficiency of pectoral qi, lung collaterals obstruction | Tongfeiluo- buzongqi decoction +NAC+ CM | NAC+ CM | 12 | ③④⑤⑦ |
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