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Evidence-Based Complementary and Alternative Medicine
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Evidence-Based Complementary and Alternative Medicine
/
2019
/
Article
/
Tab 1
/
Research Article
Effect of Naoxintong Capsules on the Activities of CYP450 and Metabolism of Metoprolol Tartrate in Rats Evaluated by Probe Cocktail and Pharmacokinetic Methods
Table 1
MS parameters of the five probe drugs and IS.
Probe drug
Precursor ion (
m
/
z
)
Product ion (
m
/
z
)
Fragmentor (V)
CE (V)
Omeprazole
346.2
136.1
80
35
Midazolam
326.1
291.1
160
25
Dextromethorphan
272.2
147.1
130
30
Phenacetin
180.1
110.1
100
17
Tolbutamide
271.1
91.1
100
17
Diazepam (IS)
285.1
193.0
130
30