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Evidence-Based Complementary and Alternative Medicine
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Special Issues
Evidence-Based Complementary and Alternative Medicine
/
2019
/
Article
/
Tab 2
/
Research Article
Effect of Naoxintong Capsules on the Activities of CYP450 and Metabolism of Metoprolol Tartrate in Rats Evaluated by Probe Cocktail and Pharmacokinetic Methods
Table 2
Mass spectra properties of the target ingredients.
Analyses
Precursor ion (
m
/
z
)
Product ion (
m
/
z
)
Fragmentor (V)
CE (V)
Metoprolol tartrate
268.2
121.1
110
20
α
-Hydroxymetoprolol
284.2
116.1
120
14
O-demethylmetoprolol
254.2
116.1
110
23
Propranolol hydrochloride (IS)
260.2
155.1
90
23