A Network Pharmacology Study on the Active Ingredients and Potential Targets of Tripterygium wilfordii Hook for Treatment of Rheumatoid Arthritis

Table 1

Cluster of rheumatoid arthritis disease PPI network.

Cluster	Score	Nodes	Edges	GENES
1	3.375	31	54	LTA, FGB, FGG, SYK, TLR4, TBP, TLR9, ITGB3, MYD88, ADAM17, NFKB2, PDGFRA, PLA2G4A, RELA, TNFRSF1A, CTLA4, REL, C1QA, HRG, C1QB, C1QC, JAK2, NCF1, PRKCD, F13A1, IRF1, STAT1, F2, IRF2, TNFRSF1B, LCK
2	2.4	4	6	CASP8, IKBKG, TNF, TNFAIP3
3	2.333	5	7	HLA-B, HLA-C, LILRB1, HLA-H, HLA-G
4	2.25	7	9	PTPRC, FCGR3A, CD4, CD3E, PTPN22, PIK3R1, CSK
5	2.2	9	11	ABL1, TNFSF11, MMP7, JAK1, CCL2, SMURF1, MMP1, BTK, CCR1
6	1.5	3	3	HFE, TFR2, TF
7	1.5	3	3	IL17RA, TRAF3IP2, IL17A