Research Article
Antifungal Activity of Crude Extract from the Rhizome and Root of Smilacina japonica A. Gray
Table 2
Activity of SJA alone and in combination with FCZ against different fungi (μg/ml) a.
| fungi | Alone | Combination | FIC index for combination | Mode of interaction | FCZb | SJA | FCZb | SJA |
| FCZ-resistant C. albicans 103 | >64 | 416 | 64 | 208 | 1.000 | addition | C. albicans SC5314 | 1 | 416 | 1 | 26 | 1.125 | indifference | Cryptococcus neoformans | 2 | 208 | 0.5 | 26 | 0.375 | synergism | C. krusei | >64 | 1665 | 8 | 208 | 0.188 | synergism | C. parapsilosis | 2 | 416 | 1 | 26 | 0.563 | addition | C. glabrata | >64 | 416 | >64 | 208 | 1.500 | indifference | C. tropicalis | >64 | 416 | 64 | 208 | 1.000 | addition |
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SJA, Smilacina japonica A. Gray; b FCZ, fluconazole. |