Qingshen Buyang Formula Attenuates Renal Fibrosis in 5/6 Nephrectomized Rats via Inhibiting EMT and Wnt/β-Catenin Pathway

Figure 1

The treatment with Qingshen Buyang Formula attenuated renal lesions and fibrosis caused by 5/6 nephrectomy. ((a)–(d)) Kidney sections of the three groups were subjected to HE staining, Masson staining, PAS staining, and Picrosirius red staining. Representative micrographs showed that Qingshen Buyang Formula ameliorated kidney injury characterized by segmental sclerosis of glomeruli, focal renal fibrosis, tubular epithelial cells vacuolization, tubular dilatation, tubular atrophy, and infiltration of inflammatory cells. Scale bar, 50 μm.

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