Study on the Antihypertensive Mechanism of Astragalus membranaceus and Salvia miltiorrhiza Based on Intestinal Flora-Host Metabolism
Table 2
Top 10 metabolic pathways of potential biomarkers.
Pathway name
Total
Hits
p
Log(p)
Holm p
FDR
Impact
Arachidonic acid metabolism
36
3
0.0069239
4.9728
0.56084
0.40424
0.36753
Tryptophan metabolism
41
3
0.0099812
4.6071
0.79849
0.40424
0.10622
Glutathione metabolism
26
2
0.033842
3.3861
1
0.72468
0.36642
Steroid hormone biosynthesis
70
3
0.041817
3.1745
1
0.72468
0.07078
Cyanoamino acid metabolism
6
1
0.066665
2.7081
1
0.72468
0
Biosynthesis of unsaturated fatty acids
42
2
0.080649
2.5176
1
0.72468
0
Taurine and hypotaurine metabolism
8
1
0.087945
2.431
1
0.72468
0
Primary bile acid biosynthesis
46
2
0.094426
2.3599
1
0.72468
0.05952
Methane metabolism
9
1
0.098413
2.3186
1
0.72468
0
Vitamin B6 metabolism
9
1
0.098413
2.3186
1
0.72468
0
Note. Total: the number of all metabolites in this pathway; Hits: The number of differential metabolites hitting this pathway; Raw p: P value obtained by enrichment analysis; Holm P: P value corrected by Holm-Bonferroni method; Impact: Impact factor from topological analysis.
