The Antioxidative Action of ZTP by Increasing Nrf2/ARE Signal Pathway

<div><i>Expression level of HO-1 and P38 proteins in cortex</i>. (a, b) Positive immunofluorescence staining of HO-1 and P38 cells in the cortex in control, LPS VE, ZTP-L, ZTP-M, and ZTP-H groups. (c, d) Fold changes of positive HO-1 and P38 immunoreactivity. <span class="nowrap"><svg height="15.3614pt" id="M7" style="vertical-align:-3.833899pt" version="1.1" viewbox="-0.0498162 -11.5275 55.0535 15.3614" width="55.0535pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.0091,0,0,-0.0091,0,-5.741)"><path d="M457 455H370L403 612H360L326 455H218L252 612H210L175 455H77L68 394H161L132 257H31L20 196H117L77 19H120L159 196H268L230 19H272L311 196H402L412 257H325L355 394H447L457 455ZM313 394L283 257H175L204 394H313Z"></path></g><g transform="matrix(.0091,0,0,-0.0091,4.432,-5.741)"><path d="M486 158C486 177 478 202 466 220C413 228 386 236 336 262C386 288 413 297 466 304C478 323 486 347 485 366C470 376 444 381 422 380C389 338 368 319 321 288C323 345 329 372 349 422C339 442 322 461 305 470C289 461 271 442 262 422C281 372 287 345 290 288C243 319 222 338 189 380C167 381 142 376 125 366C125 347 133 322 145 304C198 296 225 288 275 262C225 236 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602Z"></path></g><g transform="matrix(.013,0,0,-0.013,68.662,0)"><path d="M384 0V27C293 34 287 42 287 114V635C232 613 172 594 109 583V559L157 557C201 555 205 550 205 499V114C205 42 199 34 109 27V0H384Z"></path></g></svg>,</span> <sup>#</sup>Control<i> VS</i> LPS, <sup>*</sup>LPS<i> VS</i> Treatment (VE/ZTP-L/ZTP-M/ZTP-H).</div>

Evidence-Based Complementary and Alternative Medicine

fig3

Figure 3

Figure 3: The Antioxidative Action of ZTP by Increasing Nrf2/ARE Signal Pathway 