| | First author (year) | Species (sex) | No. of rats (intervention/control group) | Weight(g) | Model method (time) | The main points | Course of treatment | Intervention group | The main outcomes | Intergroup difference |
| | Yan (2015)[27] | Wistar rats | (8/8) | 180 ± 20 | High-fat diet (8w) | ST36, CV12 | 20 minutes, once a day, 4 weeks | Electroacupuncture: continuous waves of 20Hz of frequency and current density of 1.5V, 4mA | 1.Weight 2.Lee’s index | 1.P<0.05
2.p<0.05 | | Yin (2015)[83] | Rats | (30/30) | Not given | High-fat diet | SP6, ST36 | 10 minutes, once a day, 15 days | Electroacupuncture: continuous waves of 10Hz of frequency and current density of 1V | Lee’s index | P<0.05 | | Yin (2015)[84] | SD rats(male) | (10/10) | 180-230 | High-fat diet (6w) | BL21, CV12 | 20 minutes, once a day, 3 weeks | Electroacupuncture: disperse-dense waves of 10-100Hz of frequency | Lee’s index | P<0.01 | | Ran (2014)[47] | SD rats (male) | (10/10) | Not given | High-fat diet (8w) | Gastric and small intestine | 30 minutes, 4 weeks | Electroacupuncture: 2/15Hz, 2mA | Weight | P<0.05 | | Han (2014)[51] | SD rats (male) | (10/10) | 160 ± 10 | High-fat diet (8w) | Not given | 15 minutes, once a day, 20 days | Electroacupuncture: continuous waves of 100Hz of frequency | Weight | P<0.01 | | Cao (2014)[85] | SD rats (male) | (7/7) | 60-80 | High-fat diet (3m) | ST36, ST44 | 15 minutes, 6 days for a week, 4 weeks | Electroacupuncture: 2/15Hz of frequency and current density of 1mA | Weight | P<0.05 | | Tan (2014)[52] | SD rats (male) | (12/12) | 90 ± 10 | High-fat diet (5w) | ST25, ST40 | 20 minutes, once a day, 6 days for a week, 4 weeks | Electroacupuncture: continuous waves of 3Hz of frequency and current density of 1.5V | Lee’s index | P<0.05 | | Gao (2013)[86] | SD rats (male) | (10/10) | 190-210 | High-fat diet (10w) | ST36, SP6 | 15 minutes, once a day, 2 weeks | Electroacupuncture: disperse-dense waves of 2Hz of frequency | Weight | P<0.01 | | Yu (2013)[87] | SD rats (male) | (10/10) | Not given | High-fat diet (3m) | ST36, ST25 | 15 minutes, once a day, 6 days for a week, 39 days | Electroacupuncture: 2/15Hz of frequency and current density of 2mA | Weight | P<0.01 | | Tang (2013)[88] | C57BL/6 mice (male) | (6/6) | 20 ± 2 | High-fat diet (16w) | ST36, SP6, ST25, CV12, ST40, CV4 | 1 minute, every 10 minutes, twice a day, 10 days | Handle acupuncture: even reinforcing-reducing by twirling for 1 minute, every 10 minutes | Weight | P<0.05 | | He (2013)[63] | SD rats (male) | (7/7) | 65-80 | High-fat diet (16w) | ST36, PC6 | 15 minutes, once a day, 4 weeks | Electroacupuncture: continuous waves of 15Hz of frequency and current density of 1.5V | Weight | P<0.05 | | Lao (2013)[56] | SD rats (male/female) | (10/10) | 200-250 | High-fat diet (60d) | CV12, ST36, SP6 | 15 minutes, once a day, 1 month | Electroacupuncture: disperse-dense waves of 5-10Hz of frequency | 1.Weight 2.Lee’s index | 1.P<0.01
2.p<0.01 | | He (2013)[76] | SD rats (male) | (10/10) | 50-70 | High-fat diet (12w) | ST2, ST25, ST36, ST44 | 15 minutes, once a day, 6 days for a week, 4 weeks | Electroacupuncture: 10Hz of frequency and current density of 1.5V, 3mA | Weight | P<0.05 | | Jiang (2012)[89] | SD rats (male) | (6/6) | 50 ± 10 | High-fat diet (90d) | ST36, ST44 | Once a week, 2 weeks | Catgut implantation | 1.Weight 2.Lee’s index | 1.P<0.001
2.P<0.001 | | Luo (2012)[90] | SD rats (male) | (10/10) | 60-90 | High-fat diet (12w) | ST21, ST25, SP15, ST44 | 10 minutes, once a day, 2 weeks | Electroacupuncture: continuous waves of 10Hz of frequency and current density of 0.5V | 1.Mean weight | P<0.05 | | Liu (1998)[57] | SD rats (male) | (8/8) | 50-60 | High-fat diet (3m) | ST36, ST44 | 10 minutes, once a day, 12 days | Electroacupuncture: continuous waves of 10Hz of frequency and current density of 1.5V | 1.Weight 2.Lee’s index | 1.P<0.001
2.P<0.001 | | Wei (2002)[60] | SD rats (male) | (14/15) | 50-60 | High-fat diet (3m) | ST36, ST44 | 10 minutes, once a day, 12 days | Electroacupuncture: continuous waves of 10Hz of frequency and current density of 1.5V | 1.Weight 2.Lee’s index | 1.P<0.01
2.P<0.001 | | Yuan (2003)[91] | SD rats (male) | (8/8) | 62-71 | High-fat diet (90d) | ST36, CV12, GB41 | 15 minutes, once a day, 15 days | Electroacupuncture: continuous waves of 8Hz of frequency and current density of 1V | 1.Weight 2.Lee’s index | 1.P<0.001
2.P<0.001 | | Li (2003)[92] | SD rats (male) | (10/10) | 50 ± 5 | High-fat diet (14w) | ST36, SP6 | 30 minutes, 3 times a week, 4 weeks | Electroacupuncture: 20Hz or 100Hz of frequency and increasing density of 0.5-1-1.5mA, each intensity for 10 minutes | Weight | P<0.05 | | Tian (2005)[93] | SD rats (male) | (10/10) | 40-50 | High-fat diet (16w) | ST36, SP6 | 30 minutes, 3 times a week, 4 weeks | Electroacupuncture: continuous waves of 2Hz of frequency and increasing density of 0.5-1-1.5mA, each intensity for 10 minutes | Weight | P<0.05 | | Huo (2011)[64] | SD rats (female) | (14/10) | 180 ± 20 | High-fat diet | ST36, ST25, | Every 10 days, 30 days | Catgut implantation | 1.Weight 2.Lee’s index | 1. p≤0.01
2. p≤0.01 | | Zhao (2001)[59] | SD rats (male) | (13/13) | 50 | High-fat diet (3m) | ST36, ST44 | 20 minutes, once a day, 12 days | Electroacupuncture: continuous waves of 10Hz of frequency and current density of 1V | Weight change | P<0.01 | | Sun (2005)[65] | SD rats (male) | (12/12) | 60-100 | High-fat diet | ST36, ST44 | 10 minutes, once a day, 14 days | Handle acupuncture | 1.Weight 2.Lee’s index | 1.P<0.001
2.P<0.001 | | Chen (2005)[42] | SD rats (male) | (8/7) | 50-70 | High-fat diet (45d) | ST36, ST44 | 20 minutes, twice a day, 15 days | Handle acupuncture: lifting and thrusting for 20 minutes every 5 minutes | 1.Weight 2.Lee’s index | 1.P<0.05
2.P<0.05 | | Zhang (2006)[66] | SD rats (male) | (8/8) | 50-60 | High-fat diet (13w) | ST36, ST44 | 10 minutes, once a day, 2 weeks | Electroacupuncture: continuous waves of 10Hz of frequency and current density of 1.5V | 1.Weight 2.Lee’s index | 1.P<0.01
2.P<0.05 | | Yang (2006)[53] | Wistar rats (male) | (15/15) | 60-100 | High-fat diet (30d) | ST36, CV12 | 10 minutes, once a day, 14 days | Electroacupuncture: 10Hz of frequency and current density of 1.5V | 1.Weight 2.Lee’s index | 1.P<0.01
2.P<0.01 | | Gao (2006)[48] | SD rats (male) | (10/10) | 80 ± 10 | High-fat diet (3m) | ST36, ST44, ST25, | 10 minutes, once a day, 14 days | Electroacupuncture: continuous waves of 1Hz of frequency and current density of 1.5V | 1.Weight 2.Lee’s index | 1.P<0.01
2.P<0.01 | | Li (2006)[67] | SD rats (male) | (20/20) | 55-76 | High-fat diet (3m) | ST36, ST44 | 10 minutes, once a day, 15 days | Electroacupuncture: continuous waves of 10Hz of frequency and current density of 1.5V | 1.Weight 2.Lee’s index | 1.P<0.01
2.P<0.01 | | Zhang (2006)[94] | SD rats (male) | (6/6) | 60-90 | Referring to Liu Zhicheng’s methods | ST36, ST44 | 10 minutes, once a day, 3 weeks | Electroacupuncture: continuous waves of 10Hz of frequency and current density of 1.5V | 1.Weight 2.Lee’s index | 1.P<0.01
2.P<0.01 | | Zhong (2007)[68] | SD rats (male) | (6/6) | 50-70 | High-fat diet (3m) | ST36, ST25, SP6 | 20 minutes, once a day, 10 days | Electroacupuncture: disperse-dense waves and current density of 0.3-0.6mA | 1.Weight 2.Lee’s index | 1.P<0.01
2.P<0.01 | | Qi (2007)[77] | SD rats (male/female) | (10/10) | 170 ± 20 | High-fat diet (4w) | ST36, PC6 | 15 minutes, 14 days | Electroacupuncture: discontinuous waves of 2Hz of frequency and current density of 1.5V, 1mA | Weight | P<0.05 | | Wu (2008)[43] | Wistar rats (male) | (10/6) | 60-100 | High-fat diet | CV12, ST25, CV6, LI11, ST36 | 30 minutes, once a day, 4 times | Handle acupuncture: retaining time of 30 minutes | 1.Weight 2.Lee’s index | 1.P<0.01
2.P<0.01 | | Li (2008)[49] | SD rats (male) | (8/8) | 60 ± 10 | Referring to Liu Zhicheng’s methods | ST36, SP6 | 30 minutes, once a day, 28 days | Electroacupuncture: disperse-dense waves of 20Hz of frequency and current density of 2mA | 1.Weight 2.Lee’s index | 1.P<0.01
2.P<0.01 | | Yang (2008)[95] | Wistar rats (male) | (8/8) | 60 ± 5 | High-fat diet (30d) | ST25, ST36, ST34 | every 10 days, 3 times | Catgut implantation | 1.Weight 2.Lee’s index | 1.P<0.05
2.P<0.05 | | Yao (2004)[69] | SD rats (male) | (8/8) | 70-80 | High-fat diet (4m) | ST36, ST44, ST25, | 10 minutes, once a day, 12 days | Electroacupuncture + auricular acupuncture: continuous waves of 1Hz of frequency and current density of 1.5V | 1.Weight 2.Lee’s index | 1.P<0.05
2.P<0.01 | | Gong (2008)[96] | SD rats (male) | (15/15) | 50-70 | High-fat diet (4m) | ST36, ST44 | 15 minutes, once a day, 6 days for a week, 39 days | Electroacupuncture: 2/15Hz of frequency and current density of 1.5V, 2mA | Weight | P<0.01 | | Yang (2007)[97] | SD rats (male) | (10/10) | 55 ± 5 | High-fat diet (12w) | ST36, ST25 | 20 minutes, once a day, 15 days | Electroacupuncture: continuous waves of 5Hz of frequency | 1.Weight 2.Lee’s index | 1.P<0.05
2.P<0.05 | | Gao (2011)[98] | SD rats (male) | (12/12) | 180-200 | High-fat diet (10w) | ST36, ST25, BL20 | Electroacupuncture group: 10 minutes, once a day, 15 days; catgut implantation group: every 7 days, twice | Electroacupuncture: continuous waves of 2Hz of frequency; catgut implantation | Weight | P<0.01 | | Yu (2011)[99] | SD rats (male) | (10/10) | 150-170 | High-fat diet (8w) | ST36, SP6 | 15 minutes, once a day, 14 days | Electroacupuncture: continuous waves of 20Hz of frequency and current density of 5V | 1.Weight 2.Lee’s index | 1.P<0.01
2.P<0.01 | | Liu (2011)[100] | SD rats (male) | (10/10) | 60-100 | High-fat diet (30d) | ST36, SP6 | 10 minutes, once a day, 14 days | Electroacupuncture: continuous waves of 10Hz of frequency and current density of 2V | Lee’s index | P<0.01 | | Xu (2007)[101] | SD rats (male) | (18/18) | Not given | High-fat diet (3m) | ST36, ST44 | 15 minutes, 6 days for a week, 49 days | Electroacupuncture: 2/15Hz, 4mA | Weight | p≤0.001 | | Zhan (2000)[61] | SD rats (male) | (8/8) | 50-60 | High-fat diet (3m) | ST36, ST44 | 5 minutes, 12days | Electroacupuncture: continuous waves of 10Hz of frequency and current density of 1.5V | Weight | P<0.001 | | Tian (2005)[102] | SD rats (male) | (20/20) | 45-55 | High-fat diet (14w) | ST36 | 30 minutes, three times a week, 4 weeks | Electroacupuncture: 2-100Hz,0.5-1.0-1.5mA | Weight | P<0.001 | | Zhang (2013)[70] | SD rats (female) | (8/8) | 80 ± 10 | High-fat diet (35d) | SP6, CV12, ST40 | 15 minutes, once a day, 10 days | Electroacupuncture: disperse-dense waves of 4-20Hz of frequency and current density of 1-2V | 1.Weight 2.Lee’s index | 1.P<0.01
2.P<0.01 | | Wang (2008)[103] | SD rats (male) | (12/12) | 50-70 | High-fat diet (4w) | CV12, CV4, ST36 | Electroacupuncture group: 20 minutes, twice a day, 4 weeks; catgut implantation group: every 7 days, 4 times | Catgut implantation | 1.Weight 2.Lee’s index | 1.P<0.01
2.P<0.01 | | Yu (2008)[104] | SD rats (male) | (8/8) | 60 ± 10 | High-fat diet (6w) | ST36, ST44, ST40, SP9, CV4, CV12 | 10 minutes, once a day, 10 days | Electroacupuncture: 2/100Hz of frequency and current density of 2mA | 1.Weight growth | P<0.05 | | Chen (2012)[58] | SD rats (male/female) | (10/10) | 200-250 | High-fat diet (2m) | CV12, ST36, SP6 | 20 minutes, once a day, 1 month | Electroacupuncture: disperse-dense waves of 5-10Hz of frequency | 1.Weight 2.Lee’s index | 1.P<0.05
2.P<0.05 | | Chen (2012)[105] | SD rats (male) | (8/8) | 60 ± 10 | High-fat diet (9w) | CV4 | 15 minutes, once a day, 20 days | Handle acupuncture: retaining time of 15 minutes | Weight | P<0.05 | | Xu (2005)[71] | SD rats (male) | (8/8) | 50 | High-fat diet (3m) | ST36, ST44 | 10 minutes, once a day, 14 days | Electroacupuncture: continuous waves of 10Hz of frequency and current density of 1.5V | 1.Weight 2.Lee’s index | 1.P<0.001
2.P<0.001 | | Zhang (2012)[106] | Wistar rats (male) | (8/8) | 50 ± 5 | High-fat diet (10w) | ST36 | 20 minutes, once a day, 30 days | Electroacupuncture: continuous waves of 10Hz of frequency | 1.Weight 2.Lee’s index | 1.P<0.05
2.P<0.05 | | Luo (2013)[107] | SD rats (male/female) | (22/22) | 80-120 | High-fat diet (4m) | ST36, ST44, ST25, | 30 minutes, once a day, 12 days | Handle acupuncture: ST36,ST 25,even reinforcing-reducing by twirling for 1 minute; ST44 reducing by twirling for 0.5 minute; retaining time of 30 minutes | Weight | P<0.000l | | Liu (2003)[62] | SD rats (male) | (12/12) | 50-70 | High-fat diet (3m) | ST36, ST44 | 10 minutes, once a day, 14 days | Electroacupuncture: continuous waves of 10Hz of frequency and current density of 1.5V | 1.Weight 2.Lee’s index | 1.P<0.01
2.P<0.01 | | Tao (2013)[108] | SD rats (male/female) | (15/15) | 50 ± 5 | High-fat diet (14w) | ST36, GB41, CV12, CV4 | 15 minutes, once a day, 20 days | Electroacupuncture: continuous waves of 10Hz of frequency and current density of 1.5V | 1.Weight 2.Lee’s index | 1.P>0.05
2.P>0.05 | | Lin (2012)[109] | SD rats (male) | (6/8) | 60-70 | High-fat diet (12w) | Not given | Once a day, 30 times | Electroacupuncture: disperse-dense waves of 2/15Hz of frequency and current density of 3mA | Weight | P<0.05 | | Shao (2008)[78] | SD rats (male) | (15/15) | 70—90 | High-fat diet (16w) | Stomach area and Hunger Point | 15 minutes, once a day, 6 days for a week, 7 weeks | Electroacupuncture: disperse-dense waves of 2/15Hz of frequency and current density of 3mA | Weight | P<0.05 | | Huang (2007)[79] | SD rats (male/female) | (15/20) | 60 ± 5 | High-fat diet (12w) | SP6, ST25 | 30 minutes, once a day, 15 days | Electroacupuncture: disperse-dense waves of 2-20Hz of frequency and current density of 2-3mA | 1.Weight 2.Lee’s index | 1.P<0.05
2.P<0.05 | | Wang (2009)[54] | SD rats (male) | (12/12) | 50-70 | High-fat diet (4w) | ST36, CV12, CV4 | 20 minutes, twice a day, 4 weeks | Electroacupuncture: continuous waves of 10Hz of frequency and current density of 1.5-2.5V | 1.Weight 2.Lee’s index | 1.P<0.01
2.P<0.05 | | Hong (2003)[110] | SD rats (male) | (10/10) | 60-90 | High-fat diet (10w) | ST44, ST36, CV4 | 10 minutes, once a day, 15 days | Electroacupuncture: continuous waves of 10Hz of frequency and current density of 1.5V | 1.Weight 2.Lee’s index | 1.P<0.001
2.P<0.01 | | Zhang (2006)[111] | SD rats (male) | (8/8) | 50 ± 5 | High-fat diet (4w) | ST36, CV12, CV9, CV6 | 10 minutes, once a day, 4 weeks | Handle acupuncture: even reinforcing-reducing by twirling for 1 minute, every 10 minutes | 1.Weight 2.Lee’s index | 1.P<0.05
2.P<0.05 | | Fu (2005)[112] | SD rats (male) | (12/11) | 69-96 | High-fat diet (12w) | ST36, ST44 | 20 minutes, 15 days | Electroacupuncture: continuous waves of 10Hz of frequency and current density of 1.5V | 1.Weight 2.Lee’s index | 1.P<0.01
2.P<0.01 | | TAKEMASA SHIRAISHI (1995)[113] | Wistar rats (male) | (21/10) | 80-90 | High-fat food (31w) | Not given | Not given | Pulse duration 0.01-5.0 ms; voltage 5-40 V: frequency, single pulse or 0.5-50 Hz | Weight | P<0.01 | | Martin S. Mok (1976)[44] | Guinea pigs | (3/3) | Not given | Feeding regimen (2m) | Not given | 3 mins every day, for 3 weeks | Electroacupuncture: 100Hz | Weight | P>0.05 | | Yan (2013)[114] | SD rats (male) | (12/12) | 52 ± 9 | High-fat diet (12w) | ST36, ST44 | Once a week, 4 weeks | Catgut implantation | 1.Weight 2.Lee’s index | 1.P<0.01
2.P<0.01 | | Bo Ji (2013)[115] | Rats | (5/6) | 180-200 | High fat diet (1w) | Not given | 20 min and conducted twice, separated by an 80 min rest interval every time, lasting for 7 days | Electroacupuncture | Weight | P<0.05 | | Shen (2014)[116] | C57BL/6J mice | (28/28) | Not given | Fed D12451 rodent diet with 45 kcal% fat for eight weeks | Not given | 30 minutes, once a day, six days a week, for 4 weeks | Electroacupuncture: 2/15Hz, 1mA | Weight ration | P<0.05 | | Wu (2009)[117] | SD rats (male/female) | (15/15) | 50 ± 5 | High-fat diet (30d) | ST36, CV12 | Once a week, 4 weeks | Catgut implantation | 1.Weight 2.Lee’s index | 1.P<0.01
2.P<0.01 | | Alfredo Eduardo Orozco Terån (2003)[118] | Wistar rats (female) | (8/8) | 50-60 | High-fat diet (12w) | ST36, ST44, SP6 | 10 minutes, once a day, 10 days | Electroacupuncture: 10Hz, 1.5V | 1.Weight 2.Lee’s index | 1.P<0.001
2.P<0.001 | | Liu (2016)[80] | SD rats (male) | (10/10) | 100 | High-fat diet | ST36, LI11 | 20 minutes, once a day, 30 days | Electroacupuncture: 10Hz, 1.5mA | Weight | P<0.05 | | Si (2016)[72] | C57BL/6 mice (male/female) | (6/6) | 18 ± 2 | High-fat diet (8w) | ST25, CV4, ST36, SP6 | 10 minutes, once a day, 7 days | Electroacupuncture: disperse-dense waves of 30Hz of frequency and current density of 2-3mA | 1.Weight 2.Lee’s index | 1.P<0.05
2.P<0.05 | | Leng (2015)[119] | SD rats (male/female) | (7/7) | 50-80 | High-fat diet (12w) | ST25, SP6, ST36, CV12 | Once a day, 5 days for a session, 4 sessions | Electroacupuncture: 18Hz, 2mA | Weight | P<0.05 | | Gong (2011)[81] | SD rats (male) | (10/10) | 50-70 | High-fat diet (4m) | ST36, ST44, CV12 | 15 minutes, once a day, 6 days for a week, 39 days | Electroacupuncture: 2mA | 1.Weight 2.Lee’s index | 1.P<0.01
2.P<0.01 | | Deng (2016)[120] | C57BL/6J mice (male) | (6/6) | 9 | High-fat diet (10w) | ST36 | Every 10 days, 3 times | Catgut implantation | Weight | P<0.01 | | Sun (2013)[121] | SD rats (male) | (5/5) | 80-90 | High-fat diet (5w) | ST36, SP6 | 30 minutes, three times a day, 6 weeks | Electroacupuncture: 10Hz, 0.6ms, 0.5-1.0-1.5mA | Weight | P<0.05 | | Li (2012)[122] | SD rats (male) | (15/15) | 70 ± 10 | High-fat diet (13w) | ST36, SP6, ST25, CV12, ST40, CV4 | 10 minutes, twice a day, 9 weeks | Handle acupuncture: even reinforcing-reducing by twirling for 1 minute, every 10 minutes | 1.Weight 2.Lee’s index | 1.P<0.01
2.P<0.01 | | Tan (2008)[55] | SD rats (male) | (8/8) | 50 ± 5 | High-fat diet (14w) | SP6, ST36 | 30 minutes, once a day, 4 weeks | Electroacupuncture: disperse-dense waves of 20Hz of frequency and current density of rise of 1mA every 10 minutes from 2mA | 1.Weight 2.Lee’s index | 1.P<0.01
2.P<0.01 | | Yao (2005)[123] | SD rats (male) | (8/8) | 70-80 | High-fat diet (4m) | ST36, ST44, ST25 | 10 minutes, once a day, 12 days | Electroacupuncture: continuous waves of 1Hz of frequency and current density of 1.5V | 1.Weight 2.Lee’s index | 1.P<0.01
2.P<0.01 | | Yuan (2005)[45] | SD rats (male) | (10/16) | Not given | High-fat diet (3m) | ST36, ST44 | 15 minutes, once a day, 6 days for a week, 7 weeks | Electroacupuncture | Weight change | P<0.01 | | Su (1999)[124] | SD rats (male) | (14/16) | 50-60 | Referring to Liu Zhicheng’s methods | ST36, ST44 | 5 minutes, once a day, 12days | Electroacupuncture: continuous waves of 10Hz of frequency and current density of 1V | 1.Weight 2.Lee’s index | 1.P<0.001
2.P<0.001 | | Yin (2008)[46] | SD rats (male) | (6/5) | 50-70 | High-fat diet (7w) | ST36, CV12 | 10 minutes, once a day, 15 days | Electroacupuncture: 5Hz | 1.Weight 2.Lee’s index | 1.P<0.05
2.P<0.05 | | Liu (2007)[125] | SD rats (male) | (8/8) | 180 ± 20 | High-fat diet (8w) | ST36, ST40, CV12, ST29 | Electroacupuncture group:15 minutes, once a day, 3 weeks for a session, 3 sessions; catgut implantation group: every 15 days, 3 times | Catgut implantation | 1.Weight 2.Lee’s index | 1.P<0.05
2.P<0.05 | | Fang (2005)[126] | SD rats (male/female) | (10/10) | 180 ± 40 | High-fat diet (8w) | ST36, ST44 | 30 minutes, once a day, 4 weeks | Electroacupuncture: frequency mixing of 2-100Hz | 1.Weight 2.Lee’s index | 1.P<0.01
2.P<0.01 | | Pan (2015)[73] | SD rats | (10/10) | 180 | High-fat diet (8w) | ST25, CV12, SP9 | Every 10days, 3times | Catgut implantation | Weight | P<0.05 | | Han Li M.M (2015)[82] | SD rats (male) | (12/12) | 100-120 | High-fat diet (5w) | Not given | 30 min of electrical stimulation daily for 6 wk | Electroacupuncture: 2/15Hz, 2mA | Weight | P<0.001 | | Wen Chorng-Kai (2014)[127] | SD rats (male) | (5/5) | 130 ± 12 | High-fat diet (15w) | Not given | 20 min, once per day for 3 or 7 consecutive days | Electroacupuncture: 10Hz, 0.5-1.0mA | Weight | P<0.05 | | Si (2014)[74] | SD rats (male) | (10/10) | 160 ± 10 | High-fat diet (10w) | CV12, ST25, CV4, SP15, ST36, SP6, CV12, CV4 | 15 minutes, once a day, 20 days | Electroacupuncture: continuous waves of 100Hz of frequency | Weight | P<0.01 | | Wang (2009)[128] | Wistar rats (male) | (8/8) | 50 ± 5 | High-fat diet (10w) | The acupoints of Spleen, Stomach, and Large Intestine Channel | 20 minutes, once a day, 30 days | Handle acupuncture | 1.Weight 2.Lee’s index | 1.P<0.001
2.P<0.001 | | Ge (2007)[129] | SD rats | (19/19) | Not given | Injecting 15% monosodium glutamate, 0.2mL/10g (5d) | ST36, SP6, CV4, CV12 | 10 minutes, once a day, 28 days | Electroacupuncture: disperse-dense waves of 100Hz of frequency | Lee’s index | P<0.05 | | Wang (2005)[50] | SD rats | (20/20) | Not Given | Injecting 15% monosodium glutamate, 0.3mL/10g (5d) | ST36, SP6, CV4, CV12 | 16 minutes, once a day, 28 days | Electroacupuncture | 1.Weight 2.Lee’s index | 1.P<0.01
2.P<0.01 | | Zheng (2015)[130] | C57BL/KsJ ob/ob mice | (6/6) | Not given | Not given | ST36, SP6, CV12, CV4 | 10 minutes, once a day, 8 weeks | Electroacupuncture: continuous waves of 10-30Hz of frequency | 1.Weight 2.Lee’s index | 1.P<0.05
2.P<0.05 | | Zheng (2006)[131] | SD rats (male) | (8/8) | 551.968 ± 47.196 | Not given | ST36, ST25, CV12, SP9 | 10 minutes, twice a day, 12 weeks | Electroacupuncture: 10Hz, 1.5V | 1.Weight 2.Lee’s index | 1.P<0.001
2.P<0.01 | | Sun (2011)[75] | SD rats (male) | (10/10) | 180 | High-fat diet (6w) | ST25, ST36 | 10 minutes, once a day in the first 10 days, twice a day in the next 20 days | Handle acupuncture | 1.Weight 2.Lee’s index | 1.P<0.05
2.P<0.05 | | Wang (2018)[132] | Wistar rats (male) | (8/8) | 180-220 | High-fat diet (12w) | ST25, ST36 | 30 minutes, 5 days a week, 8 weeks | Electroacupuncture: frequency of 2 Hz/15 Hz and intensity of 1 m A | Weight | P<0.05 | | Si (2018)[133] | C57BL/6 mice (male/female) | (10/10) | 18 ± 2 | High-fat diet (8w) | ST25, CV4, ST36, SP6 | 10 minutes, once a day, 21 days | Electroacupuncture: disperse-dense waves, current density of 2-3mA | 1.Weight 2.Lee’s index | 1.P<0.01
2.P<0.01 | | Tang (2017) [134] | C57BL/6 mice (male) | (6/12) | 10.2 ± 0.68 | High-fat diet (12w) | ST36, ST44 | 20 minutes, 6 days a week, 4 weeks | Electroacupuncture: 2Hz/15 Hz HzH of frequency, current density of 0.6-1mA | Weight | P<0.01 | | Wu (2019) [135] | Rats (male) | (8/8) | 110-120 | High-fat diet (12w) | ST40 | 20 minutes, three times a week, 12 weeks | Handle acupuncture | Weight | P<0.05 | | Si (2019)[136] | C57BL/6 mice (male/female) | (10/10) | 18 ± 2 | High-fat diet (8w) | CV12, CV4, ST25, ST36, | 10 minutes, once a day, 28 days | Handle acupuncture | 1.Weight 2.Lee’s index | 1.P<0.01
2.P<0.01 | | Yao (2019)[137] | SD rats (male) | (8/8) | 70-90 | High-fat diet (14w) | ST25, CV12, ST36, SP6 | 20 minutes, once a day, 28 days | Electroacupuncture: 18 Hz HzH of frequency, current density of 2mA | Weight | P<0.05 | | Zhang (2017)[138] | C57BL/6 mice (male) | (10/10) | 22 ± 2 | High-fat diet (16w) | CV9, ST36, EX-B3 | 15 minutes, once a day, 8 weeks | Handle acupuncture | Weight | P<0.05 | | Yang (2018)[139] | Wistar rats (male) | (10/10) | Not given | High-fat diet (8w) | ST44, CV12, CV4, ST36 | 10 minutes, three times a week, 8 weeks | Electroacupuncture: 2 Hz HzH of frequency, current density of 1mA | 1.Weight 2.Lee’s index | 1.P<0.05
2.P<0.05 | | Li (2017) [140] | SD rats (male) | (8/8) | Not given | High-fat diet (5w) | CV12, ST25 | Once a week, 4 weeks | Catgut implantation | 1.Weight 2.Lee’s index | 1.P<0.01
2.P<0.01 | | Fan (2018) [141] | SD rats (male) | (7/7) | 120~150
(±30 ) | High-fat diet (7w) | CV12, ST25, CV4, ST36, SP9, ST40 | 30 minutes, once a day, 4 weeks | Handle acupuncture | 1.Weight 2.Lee’s index | 1.P<0.01
2.P<0.01 | | Lin (2018) [142] | SD rats (male) | (10/10) | 120-150 | High-fat diet (7w) | CV12, ST25, CV4, ST36, SP9, ST40 | 30 minutes, once a day, 28 days | Handle acupuncture | Weight | P<0.01 | | He (2018) [143] | SD rats (male) | (10/10) | 120~150
(±30 ) | High-fat diet (7w) | CV12, ST25, CV4, ST36, SP9, ST40 | 30 minutes, once a day, 28 days | Handle acupuncture | Weight | P<0.01 | | Li (2016) [144] | SD rats (male) | (10/9) | Not given | High-fat diet (12w) | CV12, ST25, ST36, SP6 | 20 minutes, once a day, 4 weeks | Handle acupuncture | Weight | P>0.05 | | Zhou (2016) [145] | Wistar rats (male) | (10/10) | 160 ± 20 | High-fat diet (8w) | CV4, CV12, ST36, ST40 | 10 minutes, three times a week, 4 weeks | Electroacupuncture: 2 Hz HzH of frequency, current density of 1mA | Weight | P<0.01 | | Wei (2017) [146] | SD rats (male) | (6/6) | 50-60 | High-fat diet (12w) | ST36, ST40 | 30 minutes, once a day, 4 weeks | Electroacupuncture: 2 /15Hz HzH of frequency, current density of 2mA | Weight | P<0.05 | | Wang (2016) [147] | SD rats (male) | (11/11) | 190.41 ± 2.23 | High-fat diet (10w) | CV12, CV6, ST25 | 30 minutes, once a day, 2 weeks | Electroacupuncture: current density of 1mA | 1.Weight 2.Lee’s index | 1.P<0.05
2.P<0.05 | | Xu (2017) [148] | C57BL/6 mice (male) | (8/8) | 9 | High-fat diet (10w) | ST36, ST44 | 15 minutes, once a day, 4 weeks | Electroacupuncture: 2 /15Hz of frequency, current density of 1mA | Weight | P<0.01 |
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