Do Different Species of Sargassum in Haizao Yuhu Decoction Cause Different Effects in a Rat Goiter Model?

Figure 5

Serum levels of triiodothyronine (T3), free T3 (FT3), thyroxine (T4), free T4 (FT4), thyroid-stimulating hormone (TSH), and thyrotropin-releasing hormone (THR) in rats in all groups after drug treatment for 28 days. (a), (b), (c), and (d) Both HYD-H and HYD-Y had no effect on the levels of T3, FT3, T4, and FT4 in sera of goiter rats. (e) Elevated level of TSH in sera of goiter rats could be efficiently decreased by the administration of HYD-Y. (f) There was no difference among all groups in the serum level of TRH. P<0.05 and P<0.01 versus Con; #P<0.05 and ##P<0.01 versus Mod; ΔP<0.05 and ΔΔPP<0.01 versus Eut; $P<0.05 and $$P<0.01 versus HYD-H, by one-way analysis of variance.

(a)

(b)

(c)

(d)

(e)

(f)