Do Different Species of Sargassum in Haizao Yuhu Decoction Cause Different Effects in a Rat Goiter Model?

Figure 6

Serum levels of thyrotropin-releasing hormone receptor (TSHR), TSHR antibody (TRAb), and thyroglobulin (Tg) in rats in all groups after drug treatment for 28 days. (a) HYD-Y could significantly decrease the level of TSHR in sera to compare with the other treatments. (b) Reduced level of TRAb in sera of goiter rats could be efficiently increased by the administration of HYD-H and HYD-Y. (c) Both HYD-H and HYD-Y could efficiently decrease the level of Tg in sera of goiter rats. P<0.05 and P<0.01 versus Con; #P<0.05 and ##P<0.01 versus Mod; ΔP<0.05 and ΔΔPP<0.01 versus Eut; $P<0.05 and $$P<0.01 versus HYD-H, by one-way analysis of variance.

(a)

(b)

(c)