FuFangChangTai Decoction Activates Macrophages via Inducing Autophagy

Figure 4

Activation of macrophages induced by FFCT in colon cancer cells: (a) morphology of autophagosome in RAW264.7 cells. A. Negative control, B. RAW264.7 cells were added with CSFE-labeled autophagosome extracted from FFCT-treated CT26.WT cells; (b) the autophagosome produced by FFCT-treated CT26.WT cells facilitated the expression of CD86 and CD40 on the surface of RAW264.7 cells; (c) cytokines expression in the supernatant of RAW264.7 cells cultured with autophagosomes for 48 h (TNF-α and IL-6). P < 0.05.

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