Evidence-Based Complementary and Alternative Medicine / 2019 / Article / Fig 6

Research Article

Pueraria lobata Extract Protects Hydrogen Peroxide-Induced Human Retinal Pigment Epithelial Cells Death and Membrane Permeability

Figure 6

Inhibitory effects of P. lobata extract on H2O2-induced phosphorylation of p38 MAPK and JNK in RPE cells. RPE cells were pretreated with P. lobata extract (10 μg/mL) and its single compounds (1 μM) for 30 min, followed by treatment with H2O2 (200 μM) for 30 min. Phosphorylation of p38 (a) and JNK (b) was detected by western blot analysis. Data are expressed as the mean ± SEM. (n = 4). vs. control; and vs. H2O2-induced cells, respectively.

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