Research Article
A Randomized Controlled Trial of Chuanhutongfeng Mixture for the Treatment of Chronic Gouty Arthritis by Regulating miRNAs
Table 1
Baseline data for high-throughput gene screening and RT-qPCR validation in the healthy control and CGA groups.
| | Indicators | Healthy control group (n = 30) | CGA group
(n = 60) | P-value |
| | Age | 50.00 ± 8.90 | 50.80 ± 9.00 | 0.691 | | Gender (% of males) | 28 (93.33) | 56 (93.33) | 1.000 | | BMI (kg/m2) | 25.20 ± 1.10 | 25.50 ± 1.30 | 0.281 | | Systolic pressure (mmHg) | 132.00 ± 8.00 | 133.00 ± 7.00 | 0.544 | | Diastolic pressure (mmHg) | 76.00 ± 6.00 | 77.00 ± 6.00 | 0.458 | | FBG (mmol/L) | 5.10 ± 0.60 | 5.20 ± 0.50 | 0.406 | | TC (mmol/L) | 4.90 ± 0.50 | 5.10 ± 0.50 | 0.077 | | TG (mmol/L) | 2.10 ± 0.80 | 2.20 ± 0.90 | 0.608 | | ALT (U/L) | 30.00 ± 9.00 | 31.10 ± 8.50 | 0.572 | | AST (U/L) | 25.20 ± 7.80 | 26.80 ± 8.30 | 0.382 | | eGFR(ml/min/1.73m2) | 111.00 ± 6.50 | 110.00 ± 7.50 | 0.392 | | SUA (μmol/L) | 330.00 ± 70.00 | 529.00 ± 76.00 | < 0.001 | | ESR (mm/h) | 10.00 ± 5.50 | 33.00 ± 15.70 | < 0.001 | | CRP (mg/L) | 3.10 ± 2.20 | 22.20 ± 11.70 | < 0.001 | | Pain scores | 0 | 3.60 ± 0.80 | - | | Swelling scores | 0 | 1.90 ± 0.89 | - | | Restricted movement scores | 0 | 1.90 ± 0.90 | - |
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CGA: chronic gouty arthritis; BMI: body mass index; FBG: Fasting blood-glucose; TC: total cholesterol; TG: triglyceride; ALT: alanine aminotransferase; AST: aspartate aminotransferase; eGFR: estimate glomerular filtration rate; SUA: serum uric acid; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein.
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