Research Article
Amelioration of CCl4-Induced Hepatotoxicity in Rabbits by Lepidium sativum Seeds
Figure 9
Effect of LSS on histopathological changes of liver tissues induced by CCL4 (0.5 mL/kg i.p.) and treated with LSS (400 mgs/kg bw). In rabbits sacrificed 5 weeks after experimental running as shown in (a) discrete chronic venous congestion (HEx200), (b) centrilobular fibrosis [arrows], regenerating hepatocytes and isolated vesicular steatosis (HEx100), and (c) mild parenchymal and portal inflammation [arrow] (HEx100). In rabbits sacrificed 10 weeks after experimental running as shown in (d) mild chronic venous congestion and isolated vesicular steatosis (HEx100), (e) evident chronic venous congestion [arrows] (HEx100), (f) steatosis (40%) with moderate inflammation (HEx100), and (g) portal to portal bridging fibrosis in one case [arrow] (HEx100).
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