Evidence-Based Complementary and Alternative Medicine / 2019 / Article / Tab 4

Research Article

Amelioration of CCl4-Induced Hepatotoxicity in Rabbits by Lepidium sativum Seeds

Table 4

Enzymatic activities of antioxidant enzymes and MDA of untreated, LSS administered, CCl4 treated, and LSS protected rabbits. All data were expressed as mean ± SEM. Values were statistically tested using the Student t-test and significant differences at p < 0.05 and p < 0.01 as indicated by () & () compared to normal control, by (#) & (##) compared to CCL4 after 5 weeks, and by (+) & (++) compared to CCL4 after 10 weeks, respectively.

GroupCAT
(ng/g tissue)
SOD
(ng/g tissue)
GR
(ng/g tissue)
GST
(ng/g tissue)
GPx
(ng/g tissue)
MDA (nmol/ml)

Control31.55 ± 1.9928.20 ± 1.0920.29 ± 0.9915.37 ± 1.2121.97 ± 1.706.47 ± 0.57
LS (200mg/kg bw)31.27 ± 1.8626.31 ± 1.5519.08 ± 0.7715.42 ± 0.6721.29 ± 1.286.35 ± 0.45
LS (400mg/kg bw)28.43 ± 2.0426.76 ± 1.8819.72 ± 1.2815.55 ± 1.4320.31 ± 0.746.35 ± 0.60
CCl4 (5 wk.)14.75 ± 2.5814.06 ± 1.3913.58 ± 0.6110.41 ± 1.0814.09 ± 0.9912.73 ± 1.06
% of Change-53- 50- 33- 32- 3596
CCl4 (10 wk.)16.82 ± 1.5717.67 ± 2.0212.77 ± 1.369.40 ± 0.7311.52 ± 1.8214.27 ± 1.07
% of Change- 46- 37- 37- 39- 47120
CCl4 + LS (200mg/kg bw) 5 wk28.46 ± 2.01##27.20 ± 0.94##18.92 ± 0.93##14.72 ± 1.18##20.09 ± 1.12##6.67 ± 0.46##
% of Change9393394142- 47
CCl4 + LS (400mg/kg bw) 5 wk25.19 ± 1.77++22.31 ± 1.40++18.13 ± 0.94++13.04 ± 1.31++19.41 ± 1.92++7.13 ± 0.72++
% of Change7058332537- 44
CCl4 + LS (200mg/kg bw) 10 wk28.72 ± 2.01##27.96 ± 2.22##19.49 ± 0.96##14.92 ± 1.58##20.06 ± 1.79##5.69 ± 0.46##
% of Change7058525874- 60
CCl4 + LS (400mg/kg bw) 10 wk29.19 ± 1.70++26.10 ± 1.43++18.87 ± 1.73++13.78 ± 0.86++19.06 ± 1.41++6.19 ± 0.52++
% of Change7347474665- 56

We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.