Erjingwan Extracts Exert Antiaging Effects of Skin through Activating Nrf2 and Inhibiting NF-B

Figure 8

EJW extracts restore the expression of COL1A2 by reducing the MMP1 expression. (a) HFF cells were seeded into the 6-well plates and exposed to 0.015% H₂O₂ for 15 min. The expressions of COL1A2 and MMP1 at 24 h were examined by Western blotting analysis. (b, c) At 48 h, the expressions of COL1A2 and MMP1 were assessed by RT-qPCR and Western blotting analysis. The concentration of EJW was 200μg/mL. # indicates the significant difference between control group and model group, and indicates the significant difference between model group and EJW group. and # P<0.05; and ## P<0.01; and ### P<0.001; and #### P<0.0001. Data were shown as mean ± SD.

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