Erjingwan Extracts Exert Antiaging Effects of Skin through Activating Nrf2 and Inhibiting NF-B

Figure 9

EJW extracts activate Nrf2 and inhibit NF-κB to improve the aging HFF cells. (a, b) HFF cells were seeded into the 6-well plates and then exposed to 0.015% H₂O₂ for 15 min. The expression of HO-1 was detected by RT-qPCR, and the expressions of p-NF-κB, NF-κB, p-IκBα, IκBα, and p-Nrf2 were examined by Western blotting analysis. (c) Data were pooled from three independent experiments. # indicates the significant difference between control group and model group, and indicates the significant difference between model group and EJW group. and # P<0.05; and ## P<0.01; and ### P<0.001; and #### P<0.0001.

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