Effects of Xingpi Kaiyu Fang on ATP, Na/K-ATPase, and Respiratory Chain Complexes of Hippocampus and Gastrocnemius Muscle in Depressed Rats

Table 4

Changes of gastrocnemius muscle complex I, II, III, and IV activities.

	Complex I	Complex II	Complex III	Complex IV
14^th day
Control
CUMS
CUMS+XPKYF 3.6g/kg
CUMS+XPKYF 7.2g/kg
CUMS+XPKYF 14.4g/kg
CUMS+ sertraline 4.5mg/kg
42^nd day
Control
CUMS
CUMS+XPKYF 3.6g/kg
CUMS+XPKYF 7.2g/kg
CUMS+XPKYF 14.4g/kg
CUMS+ sertraline 4.5mg/kg

Note: the CUMS procedures were performed 30 minutes after drug administration usually by gavage between 9am and 10am. Values were presented as mean ± SEM. n=6 rats per group. P<0.05 versus control group; P<0.01 versus control group; ^△P<0.05 versus CUMS group.