Targeting Ovarian Cancer Cell Cytotoxic Drug Resistance Phenotype with Xanthium strumarium L. Extract
XFC extract alters ES-2 and SKOV-3 cell cycle division. Human ovarian clear cell carcinoma (ES-2) and human ovarian adenocarcinoma (SKOV-3) cells were cultured, followed by treatments with various concentrations of XFC in serum-free media for 24 hours, fixation, and by PI staining. (a) Data acquisition was performed by flow cytometry as described in Section 2 in order to assess cell cycle phases. (b) Data analysis was also performed in order to assess the levels of cells in sub-G1, G0/G1, S, and G2/M phases. Significance: ,, versus the negative control.