Two-Week Repeated Oral Dose Toxicity Study of Mantidis Ootheca Water Extract in C57BL/6 Mice

Table 6

Serum biochemical values in male mice after 2 weeks of repeated oral administration of MO.

Parameters	Group (mg/kg/day)
	0	50	150	450
CRE (mg/dL)	1.620 ± 0.228	1.320 ± 0.259	1.560 ± 0.451	1.600 ± 0.678
GLU (mg/dL)	172.000 ± 6.218	152.500 ± 12.793	159.750 ± 29.113	161.250 ± 33.925
GOT (U/L)	85.000 ± 5.354	72.500 ± 8.515	81.500 ± 15.000	72.750 ± 4.646
GPT (U/L)	55.000 ± 9.566	53.800 ± 9.039	64.400 ± 37.226	52.000 ± 12.268
BUN (mg/dL)	25.675 ± 2.712	24.920 ± 2.543	24.240 ± 2.237	25.780 ± 2.160
TBIL (mg/dL)	0.725 ± 0.222	0.900 ± 0.082	1.050 ± 0.173	1.025 ± 0.126

CRE, creatinine; GLU, glucose; GOT, glutamic oxaloacetic transaminase; GPT, glutamic pyruvic transaminase;
BUN, blood urea nitrogen; TBIL, total bilirubin.
Values are expressed as means ± SD of five mice at sacrifice.
Significantly different from the normal control at p < 0.05.