Acupuncture for Premenstrual Syndrome at Different Intervention Time: A Systemic Review and Meta-Analysis

Table 1

Characteristics of the included studies.

Study	Sample; E/C	Experiment	control	Acupoints	Intervention time	Outcomes	AE
Liu 2006 [10]	44/44	ACE	Medicine	PC6, SP6, CV4, CV17, LR3	15 days before MS	IR	NR
Xu 2005 [11]	54/48	AI+AT	Medicine	AI in SP6, ST36 and AT in L14, LR6, RN4, RN6, EX-HN5	10 days before MS	IR	NR
Fang 2008 [12]	47/43	AT	Medicine	DU24, LR3+L14, SP6	14-16 days before MS	IR, symptom score, HAMA score	NR
Li 2011 [13]	15/15	AT	Medicine	RN12, RN10, RN4, RN6, SP15, ST29	7 days before MS	symptom score, SCL-90 scores, IR	NR
Yu 2006 [14]	33/32	AT	sham AT	DU20, EX-HN3, EX-HN5, SP6, SP10	7 days before MS	symptom score; Uncomfortable Days; IR	hypomenorrhea
Zhang 2017 [15]	30/30/30	AT	Medicine/ACE+Auricular points	LR3, SP6, PC6, LA14, BL18	14 days before MS	symptom score; SCL-90 score; IR, E2, P	NR
Hong 2002 [16]	35/31	EA	Medicine	Scalp acupuncture: Frontal line, middle line of vertex	three times per week	symptom score, IR	NR
Xu 2006 [17]	30/30	AT	Medicine	DU8, DU6, DU4, BL18, BL20, BL22, BL47, BL49, BL51	14 days before MS	IR	NR
Sun 2004 [18]	30/31	AT	Medicine	D20, RN17, RN4, SP6, PC6, LR3	14 days before MS	symptom score, IR	NR
Xu 2008 [19]	100/100	AT	Medicine	GB20, DU15	When the symptoms occurred	IR	NR
Zhang 2016 [20]	35/35/35	AT+Intradermal needle	non acupoint superficial AT; sham AT	AT:DU8, EX-HN3, RN12, RN10, BL24, RN4, EX-CA1, SP6, KI6, LI4, LR3; Intradermal needle:BL15, BL18,; BL23	AT:3 per week; Intradermal needle:2 times per week	HAMA/WHOQOL-BREF/DRSP scale; IR	Hematoma, pain;redness, itching, in the skin, pain
Zeng 2013 [21]	80/80	AT+Medicine	Medicine	LR3, K13, RN6, BL18, RN17, SP6	10 days before MS	IR	NR
Habek 2002 [22]	18/17	AT	sham AT	DU20, L14, LR3, RN3, RN4, RN6, PC6, GB34, BL23	Luteal phase	IR	Hematoma
Shin 2009 [23]	10/10/10	Korea hand AT	no treatment	A5, A6, A8, A12, A16, A18, N18, F6	1 per 3 days	symptom score	None
Kim 2005 [24]	10/10	AT	sham AT	SP6, RN9	2 per week	symptom score	NR

(ACE: acupuncture catgut embedding, A/C: acupuncture group versus control group, AE: adverse events, AI: acupoint injection, AT: acupuncture, DRSP score: Daily record of severity of problems scale, E2: estradiol, ET: electroacupuncture, HAMA: Hamilton anxiety scale, IR: effective rate, MS: menstruation, NR: not reported, P: progesterone, SCL-90: SymptomChecklist90, WHOQOL-BREF scale:WHO Quality of Life-BREF scale)