GC-MS Analysis and Inhibitory Evaluation of Terminalia catappa Leaf Extracts on Major Enzymes Linked to Diabetes

Table 1

IC₅₀, V_max, and K_m values of T. catappa leaf extracts on α-glucosidase and α-amylase.

	α-Glucosidase			α-Amylase
	IC50 (mg/mL)	Vmax (mM/min)	Km (mM)	IC50 (mg/mL)	V max (mM/min)	Km (mg)
TCE	3.78 ± 0.26^c	0.13	0.19	0.24 ± 0.08^a	0.013	2.27
TCA	3.28 ± 0.47^b	0.10	0.77	0.75 ± 0.14^b	0.016	2.22
Acarbose	2.23 ± 0.21^a	—	—	0.85 ± 0.18^b	—	—
Control	—	0.35	0.19	—	0.025	0.43

Data are represented as mean ± SD (n = 3). Values with different superscripts down a column are significantly different at . IC₅₀: half maximal inhibitory concentration; V_max: maximum velocity; K_m: Michaelis constant.