Chinese Medicine FTZ Recipe Protects against High-Glucose-Induced Beta Cell Injury through Alleviating Oxidative Stress

Figure 3

Effect of FTZ on the protein expression of Bcl-2 and caspase-3 in the pancreatic tissue of the HFHSD diabetic rats. The levels of protein expression of Bcl-2 and Caspase-3 in pancreatic islets of HFHSD diabetic rats were assayed as described in the text. Rats were fed with HFHSD for 16 weeks and injected with 36 mg/kg STZ ip at the end of the 6th week. FTZ and rosiglitazone were administered for 8 weeks. The protein expression of Bcl-2 and caspase-3 in the pancreatic tissue of the HFHSD diabetic rats was tested by Western blot (a). The protein expression relative intensity of Bcl-2 (b) and caspase-3 (c). Compared with control group^▲▲P<0.01. Compared with model group, P<0.05; P<0.01.

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