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Study ID | Diseases | Sample T/C | Age (years) | Gender M/F | Treatment | Duration | Main outcomes |
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Cheng Y 2016 [10] | fever | 41/40 | T:38.03 ± 14.65 C:37.21 ± 15.43 | T:22/19 C:20/20 | Clearing heat and removing toxicity formula | 3 d | Fever clearance time, AE |
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Xie JH 2017 [11] | fever | 48/48 | T:36.7 ± 6.7 C:39.4 ± 2.1 | T:25/23 C:20/28 | Clearing heat and removing toxicity formula | 3 d | symptoms improving, AE |
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Li Y 2012 [12] | AIDS | 36/36 | 18-70 | 46/26 | Improving immunity formula | 180 d | CD4 |
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Cheng Y 2017 [13] | non-alcoholic fatty liver | 48/48 | T:45.07 ± 11.23 C:41.65 ± 9.38 | T:23/17 C:25/15 | Invigorating spleen, regulating Qi and resolving dampness formula | 24 w | Free fatty acids, ALT, AE |
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Fu CH 2014 [14] | migraine | 150/78 | T:37.11 ± 11.96 C:34.97 ± 10.40 | T:33/96 C:12/52 | Modified Rhizoma Chuanxiong releasing pain decoction or Wuzhuyu decoction | 12 w | No. and degree of headache |
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Xu YL 2011 [15] | migraine | 24/24 | 18~65 | T:5/19 C:11/13 | Regulating liver, dispelling wind and removing blood stasis formula | 12 w | No. and degree of headache, AE |
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Zhang Y 2013 [16] | migraine | 86/42 | T:23 ~ 56 C:24 ~ 54 | T:23/63 C:11/31 | Modified Chuanxiong Dingtong decoction | 12 w | No. of headache, PSQI scale, EO |
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Geng YY 2015 [17] | asthma | 40/20 | T:3.62 ± 0.88 C:3.37 ± 0.90 | T:30/10 C:17/3 | Nourishing Qi to invigorate spleen and invigorating the kidney formula | 12 w | No. of asthma attacks, AE |
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He JS 2012 [18] | HBV carrier | 200/100 | T:33.6 ± 7.1 C:34.4 ± 8.2 | T:137/63 C:60/40 | Notifying kidney and spleen formula | 52 w | HBV DNA, HBeAg, HBsAg, AE |
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Li HZ 2012 [19] | HBV carrier | 200/100 | T:34.33 ± 6.22 C:34.39 ± 8.18 | T:118/82 C:59/41 | Notifying and clearing kidney formula | 52 w | HBV DNA, HBeAg |
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Ni W 2015 [20] | HBV carrier | 40/20 | 36. 24 ± 8. 22 | T:19/21 C:12/8 | Notifying and clearing kidney formula | 48 w | HBV DNA, HBeAg, AE |
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Peng DT 2016 [21] | HBV carrier | 50/25 | T:34.67 ± 5.12 C:32.20 ± 3.95 | T:24/26 C:14/11 | Notifying kidney and detoxifying formula | 48 w | HBV DNA, HBeAg, HBsAg, AE |
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Xing YF 2012 [22] | HBV carrier | 200/200 | T:34.33 ± 6.22 C:34.39 ± 8.18 | T:113/78 C:112/75 | Notifying and clearing kidney formula | 52 w | HBV DNA, AE |
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Zheng YJ 2012 [23] | HBV carrier | 60/60 | T:35.0 ± 5.0 C:34.0 ± 6.0 | T:42/18 C:45/15 | Notifying kidney and spleen formula | 48 w | HBV DNA, HBeAg, AE |
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Zhang ZE 2013 [24] | HBV recrudescence | 23/23 | T:37.7 ± 12.5 C:38.1 ± 12.0 | T:12/11 C:13/10 | Notifying kidney and spleen formula | 48 w | HA, PCIII, AE |
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Xu F 2013-1 [25] | depressed | 50/50 | T:30.43 ± 3.43 C:30.07 ± 3.34 | - | Benefiting brain and relieving depression formula | 6 w | Edinburgh Postnatal Depression Scale, AE |
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Xu F 2013 [26] | depressed | 47/46 | - | - | Ease powder | 6 w | cognitive function, AE |
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Zhao L 2014 [16] | HCV | 102/102 | 1b:54.7 ± 12.47 other:49.5 ± 16.7 | T:81/48 C:24/20 | Qizhu (astragalus and atractylodes) granules | 48 w | HCV RNA |
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Zhao L2014-1 [27] | HCV | 96/96 | T:53.47 ± 12.80 C:53.27 ± 13.24 | T:39/57 C:34/52 | Qizhu (astragalus and atractylodes) granules | 48 w | HCV RNA, AE |
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Chen SQ 2017 [28] | COPD | 60/60 | T:65.06 ± 5.05 C:66.08 ± 6.04 | T:29/31 C:32/28 | Modified Erchen decoction combined with antibiotics, bronchiectasis and oxygen uptake | 14 d | Pulmonary function, IgA, AE |
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Xie WY 2017 [29] | COPD stable period COPD acute period | 60/60 60/60 | T:65.05 ± 5.07 C:68.07 ± 6.15 T:68.12 ± 5.07C:68.11 ± 6.06 | T:33/27 C:31/29 T:32/28 C:30/30 | Modified Erchen decoction combined with antibiotics, bronchiectasis and oxygen uptake | 14 d | Pulmonary function |
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Shang LZ 2017 [30] | COPD | 100/100 | T:69.48 ± 9. 05C:70.39 ± 8. 84 | T: 57/43 C: 55/45 | Modified Erchen decoction combined with antibiotics, bronchiectasis and oxygen uptake | 14 d | Pulmonary function |
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Hu WH 2015 [31] | diabetic peripheral neuropathy | 50/50 | T:54.5(43-68) C:53.2(46-69) | T:24/26 C:22/28 | Eliminating arthralgia and promoting blood circulation granules combined with methycobal and antidiabetics | 8 w | Pain, neurological function |
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Li M & Yang MH [32–40] | Parkinson’s disease | 60/60 | T:66.6 ± 1.2 C:67.3 ± 1.2 | T:31/27 C:42/20 | Notifying the kidney and promoting blood circulation formula combined with madopar | 36 w | Unified Parkinson’s disease rating scale, AE |
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Liu J 2012 [41] | depression | 30/30 | T:40.13 ± 9.72 C:41.25 ± 9.59 | T:14/18 C:13/20 | Relieving depression granules combined with paroxetine | 8 w | HAMD Scale, AE |
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Pang LJ 2013 [42] | angina pectoris | 35/35 | T:57.2 ± 9.2 C:60.13 ± 3.8 | T:15/15 C:15/15 | Promoting blood circulation and resolving turbidity formula combined with aspirin | 8 w | Pain, attacks, ECG, nitro-glycerine |
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Shuang XP 2014 [43] | myasthenia gravis | 20/18 | T:22-60 C:20-59 | T:8/12 C:7/11 | Notifying Qi and dehumidification formula combined with prednisone and pyridine bromide | 10 w | Myasthenia gravis scale |
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Song JK 2016 [44] | herpes simplex keratitis (liver-wind and deficiency of liver-Yin) | 35/40 38/40 | T:36.5 ± 7.3 C:38.2 ± 8.6 T:46.5 ± 8.2 C:44.2 ± 7.6 | T:17 /16 C:16 /15 T:15/17 C:16 /18 | Clearing or softening liver formula combined with ganciclovir | 7 d | Symptoms, laboratory test, AE |
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Xie WN 2016 [45] | HBV | 40/40 | T:27.43 ± 5.75 C:28.72 ± 6.42 | T:30/10 C:31/9 | Notifying kidney and spleen formula combined with lamivudine | 48 w | HBV DNA, HBeAg, AE |
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Ye YA 2012 [46] | HBV | 295/295 | - | - | Regulating liver and blood and notifying spleen/Regulating liver, detoxification and dehumidification combined with adefovir dipivoxil | 48 w | HBeAg |
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Zhan BL 2013 [47] | HBV | 30/30 | T:34.26 ± 9.41 C:36.19 ± 10.29 | T:21/9 C:19/11 | Regulating liver and blood and notifying spleen/Regulating liver, detoxification and dehumidification combined with adefovir dipivoxil | 48 w | HBV DNA, HBeAg, AE |
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Zhang PJ 2013 [48] | liver cirrhotic ascites | 56/56 | T:42.7 ± 6.42 C:44.72 ± 5.48 | T:32/24 C:30/26 | Alleviating water retention formula | 28 d | Liver function |
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