Effect of <i>Rhus verniciflua</i> Extract on IgE-Antigen-Mediated Allergic Reaction in Rat Basophilic Leukemic RBL-2H3 Mast Cells and Passive Cutaneous Anaphylaxis in Mice

<div>Effect of <i>Rhus verniciflua</i> extract (RVE) on the expression of COX-2 and p-cPLA2 genes in RBL-2H3 mast cells. (a) PGD<sub>2</sub> levels in the culture medium of IgE-sensitized RBL-2H3 mast cells treated with RVE. (b, c) Immunoblot analysis performed with anti-COX-2 and p-cPLA2 antibodies. <i>α</i>-Tubulin was used as protein loading control. Results are expressed as mean ± SE of at least five independent experimental results that were tested by analysis of variance with Bonferroni’s post hoc testing; <svg height="14.9569pt" id="M14" style="vertical-align:-3.429399pt" version="1.1" viewbox="-0.0498162 -11.5275 49.4726 14.9569" width="49.4726pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.0091,0,0,-0.0091,0,-5.741)"><path d="M457 455H370L403 612H360L326 455H218L252 612H210L175 455H77L68 394H161L132 257H31L20 196H117L77 19H120L159 196H268L230 19H272L311 196H402L412 257H325L355 394H447L457 455ZM313 394L283 257H175L204 394H313Z"></path></g><g transform="matrix(.013,0,0,-0.013,4.946,0)"><path d="M570 304C570 398 525 448 414 448C385 448 343 445 312 434L329 511L321 518C297 504 262 482 244 460L233 411C195 397 159 381 128 358L135 332C160 347 189 360 224 373L111 -147C97 -210 84 -218 17 -231L13 -257L254 -247L259 -218L233 -216C183 -212 177 -202 189 -142L218 -1C238 -10 266 -12 283 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Evidence-Based Complementary and Alternative Medicine

fig4

Figure 4

Figure 4: Effect of <i>Rhus verniciflua</i> Extract on IgE-Antigen-Mediated Allergic Reaction in Rat Basophilic Leukemic RBL-2H3 Mast Cells and Passive Cutaneous Anaphylaxis in Mice 

Figure 4 | Effect of Rhus verniciflua Extract on IgE-Antigen-Mediated Allergic Reaction in Rat Basophilic Leukemic RBL-2H3 Mast Cells and Passive Cutaneous Anaphylaxis in Mice 